Levest® – A lower cost,1–3 bioequivalent alternative to Microgynon® 304

  • Levest® is a monophasic combined oral contraceptive (COC), containing 150mcg levonorgestrel and 30mcg ethinylestradiol
  • Levest® contains the same active ingredients and is bioequivalent to Microgynon® 30, therefore, following appropriate patient assessment and review, it may be prescribed in place of Microgynon® 303–5
  • Each pack of Levest® contains 3 x blister strips of 21 tablets for 3 cycles of contraceptive cover6
levest
Please refer to the full Summary of Product Characteristics (SmPC) before prescribing.

Summary of Product Characteristics and Patient Information Leaflet
Summary of Product Characteristics:
https://www.medicines.org.uk/emc/product/9565/smpc

Patient Information Leaflet:
https://www.medicines.org.uk/emc/product/9565/pil

Additional Prescriber Resources
Whether your patient is starting the pill for the first time, or you are talking to her about changing from her current brand of contraceptive to Levest®, it can be useful to have information and materials to hand to counsel patients. The following assets can be downloaded/edited at your discretion for use during a consultation:

The full NICE Clinical Knowledge Summary for contraceptive prescribing for combined oral contraceptives, including UK Medical Eligibility Criteria may be found here.

References

  1. Data on File: Contraceptives Cost Saving Data. Feb 2019;
  2. MIMS. Microgynon 30 (Bayer plc). Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/microgynon-30 (accessed July 2020);
  3. Morningside Healthcare Ltd. Levest® PI. May 2020. LEV/PI/27333-0520;
  4. MHRA. UK PAR Femicept 150/30 coated tablets, Levest 150/30 coated tablets (levonorgestrel, ethinylestradiol). Available at: https://www.geneesmiddeleninformatiebank.nl/Pars/h102777.pdf (accessed July 2020);
  5. Bayer plc. Microgynon 30 tablets. Summary of Product Characteristics. June 2020. Available at: https://www.medicines.org.uk/emc/product/1130/smpc (accessed July 2020);
  6. MIMS. Levest. Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/levest (accessed July 2020).

Microgynon® 30 chosen as a comparator as it is the license reference product for Levest®.4