Yacella® – A lower cost,1–3 bioequivalent alternative to Yasmin®4

  • Yacella® is a monophasic combined oral contraceptive (COC), containing 0.03mg ethinylestradiol and 3mg drospirenone
  • Yacella® contains the same active ingredients and is bioequivalent to Yasmin®, therefore, following appropriate patient assessment and review, it may be prescribed in place of Yasmin®3–5
  • Each pack of Yacella® contains 3 x blister strips of 21 tablets for 3 cycles of contraceptive cover6

Please refer to the full Summary of Product Characteristics (SmPC) before prescribing.

Summary of Product Characteristics and Patient Information Leaflet
Summary of Product Characteristics:

Patient Information Leaflet:

Additional Prescriber Resources
Whether your patient is starting the pill for the first time, or you are talking to her about changing from her current brand of contraceptive to Yacella®, it can be useful to have information and materials to hand to counsel patients. The following assets can be downloaded/edited at your discretion for use during a consultation:

The full NICE Clinical Knowledge Summary for contraceptive prescribing for combined oral contraceptives, including UK Medical Eligibility Criteria may be found here.


  1. Data on File: Contraceptives Cost Saving Data. Feb 2019;
  2. MIMS. Yasmin (Bayer plc). Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/yasmin (accessed July 2020);
  3. Morningside Healthcare Ltd. Yacella® PI. July 2020. YAC/PI/27333-0720;
  4. MHRA. UK PAR Yacella 0.03 mg/3 mg tablets. December 2015. Available at: https://mhraproductsproduction.blob.core.windows.net/docs/da60a925891cddb6949eeca3625262f534a3a163 (accessed May 2020);
  5. Bayer plc. Yasmin film-coated tablets 0.03mg/3mg. Summary of Product Characteristics. December 2018. Available at: https://www.medicines.org.uk/emc/product/1607/smpc (accessed July 2020);
  6. MIMS. Yacella. Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/yacella (accessed July 2020).

Yasmin® chosen as a comparator as it is the license reference product for Yacella®.4