About Levest®

Your healthcare provider has prescribed Levest® as your combined oral contraceptive.

If you are starting Levest® for the first time, please carefully read the Patient Information Leaflet (PIL) provided inside the pack.

Understanding how to take Levest® correctly and what might make it less effective is essential to prevent an unwanted pregnancy.

If you misplace the PIL you can download a replacement here.

Why was I given Levest®?
If you want to find out more about why Levest® was chosen as your contraceptive pill, please talk to your doctor or healthcare provider. They will be able to explain in greater detail why Levest® has been selected as the right choice for your contraception.

If you received Microgynon® 30 previously
Changing to Levest® is as simple as getting used to the new packaging – you’ll take the same number of tablets each month, and request repeat prescriptions in the same way as when you took Microgynon® 30.1,2 When taken correctly, Levest® is just as effective at preventing pregnancy as Microgynon® 30.3,4

Levest® contains the same active ingredients in the same amounts as Microgynon® 30, and is therefore considered to work in the same way.1—4

If you still have any concerns about your change of brand, please talk to the healthcare provider who prescribed you this product.

Other Concerns?
Only your healthcare provider knows your full medical history, so if there is any information in the Patient Information Leaflet that you want to know more about or worries you, please talk to your doctor or healthcare provider for advice and guidance.

What Levest® tablets are and what they are used for
Levest® coated tablets are a combined oral contraceptive and belongs to a group of products often referred to as “the Pill”.Levest® contains two hormones: oestrogen (Ethinylestradiol) and progestogen (Levonorgestrel).These hormones prevent you from getting pregnant, just as your natural hormones would prevent you from conceiving again when you are already pregnant.
Before you take Levest®
In your Patient Information Leaflet, several situations are described where you should stop using Levest®, or where the reliability of Levest® may be decreased. In such situations you should either not have intercourse or you should take extra non-hormonal contraceptive precautions, e.g., use a condom, or another barrier method. Do not use rhythm or temperature methods. These methods can be unreliable because Levest® alters the monthly changes of the cervical mucus.Levest®, like other hormonal contraceptives, does not protect against HIV infection (AIDS) or any other sexually transmitted disease.Do not take Levest®

  • If you are allergic (hypersensitive) to any of the ingredients of Levest®
  • If you have (or have had in the past) a blood clot (thrombosis) in a blood vessel of the leg, lung (embolus) or other organs
  • If you have (or have had in the past) a heart attack or stroke
  • If you have (or have had in the past) a disease that can be a predictor of a heart attack (for example, angina pectoris, which causes severe pain in the chest) or of a stroke (for example, a transient slight stroke with no residual effects)
  • If you have a disease that may increase the risk of a thrombosis in the arteries. This applies to the following diseases:
  • Diabetes mellitus with damaged blood vessels
  • Very high blood pressure
  • A very high level of fat in the blood (cholesterol or triglycerides)
  • If you have a disturbance of blood clotting (for example, protein C deficiency)
  • If you have (had) a certain form of migraine (with so-called focal neurological symptoms)
  • If you have (had) an inflammation of the pancreas (pancreatitis)
  • If you have or have had in the past a liver disease and your liver function is still not normal
  • If you have or have had a tumour in the liver
  • If you have (had) or if you are suspected of having breast cancer or cancer of the genital organs
  • If you have any unexplained bleeding from the vagina
  • If you have absence of menstrual period and the cause is unknown

When to consult your doctor

Stop taking Levest and tell your doctor immediately if after taking Levest you notice possible signs of thrombosis, such as

  • any unusual, severe or long-lasting headache or worsening of migraine
  • partial or complete blindness or double vision
  • sudden pain and/or swelling in one of your legs
  • sudden breathlessness
  • sudden cough without an obvious cause
  • sudden severe pain in the chest which may reach the left arm
  • difficulty in speaking or inability to speak
  • weakness, strange feeling, or numbness in any part of the body
  • a feeling of dizziness or spinning
  • collapse with or without focal seizure
  • motor disturbances
  • sudden severe abdominal pain

Please read your Patient Information Leaflet carefully for additional information on blood clots and how to recognise them, and special warning signs and precautions that you can take as well as other health conditions that may be associated with taking the pill.

How to take Levest®
Always take Levest® exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.Take one tablet of Levest® every day, if necessary with a small amount of water. You may take the tablets with or without food, but you should take the tablets every day around the same time.The strip contains 21 tablets. Next to each tablet is printed the day of the week that it should be taken. If, for example you start on a Wednesday, take a tablet with “WED” next to it. Follow the direction of the arrow on the strip until all 21 tablets have been taken. Then take no tablets for 7 days. In the course of these 7 tablet-free days (otherwise called a stop or gap week) bleeding should begin. This so-called “withdrawal bleeding” usually starts on the 2nd or 3rd day of the gap week. On the 8th day after the last Levest® tablet (that is, after the 7-day gap week), start the following strip, even if the bleeding has not stopped. This means that you should start the following strip on the same day of the week and that the withdrawal bleed should occur on the same days each month.

If you use Levest® in this manner, you are also protected against pregnancy during the 7 days that you are not taking a tablet.

Starting the first pack of Levest®

  • If you have not used a contraceptive with hormones in the previous month
    Begin with Levest® on the first day of the cycle (that is the first day of your menstruation). If you start Levest® on the first day of your menstruation you are immediately protected against pregnancy. You may also begin on day 2-5 of the cycle, but then you must use extra protective measures (for example, a condom) for the first 7 days.
  • Changing from another combined hormonal contraceptive, or combined contraceptive, vaginal ring or patch.
    You can start Levest® preferably on the day after the last active tablet (the last tablet containing the active substance) of your previous pill, but at the latest on the day after the tablet-free days of your previous pill finish (or after the last inactive tablet of your previous pill). When changing from a combined contraceptive vaginal ring or patch, follow the advice of your doctor.
  • Changing from a progestogen-only-method (progestogen-only pill, injection, implant or a progestogen-releasing IUD)
    You may switch any day from the progestogen-only pill (from an implant or the IUD on the day of its removal, from an injectable when the next injection would be due) but in all of these cases you must use extra protective measures (for example, a condom) for the first 7 days of tablet-taking.
  • After a miscarriage
    Follow the advice of your doctor.
  • After having a baby
    After having a baby, you can start Levest® between 21 and 28 days later. If you start later than day 28, you must use a so-called barrier method (for example, a condom) during the first seven days of Levest® use. If, after having a baby, you have had intercourse before starting Levest® (again), you must first be sure that you are not pregnant or you must wait until the next menstrual bleed.

Let your doctor advise you in case you are not sure when to start.

If you are breastfeeding and want to start Levest® after having a baby. Read the section on “Breast feeding” in your Patient Information Leaflet.

Bleeding between periods

During the first few months that you are taking Levest, you may have unexpected bleeding (bleeding outside the gap week). If this bleeding lasts longer than a few months, or if it begins after some months, your doctor must investigate the cause.

What you must do if no bleeding occurs in the gap week

If you have taken all the tablets correctly, have not had vomiting or severe diarrhoea and you have not taken any other medicines, it is highly unlikely that you are pregnant.

If the expected bleeding does not happen twice in succession, you may be pregnant. Contact your doctor immediately. Do not start the next strip until you are sure that you are not pregnant.

Missed pills
  • If you are less than 12 hours late in taking your pill, the protection from pregnancy is not reduced. Take the tablet as soon as you remember, and further pills again at the usual time.
  • If you are more than 12 hours late taking a tablet, the protection from pregnancy may be reduced. The greater the number of tablets that you have forgotten, the greater is the risk that the protection from pregnancy is reduced.

The risk of incomplete protection against pregnancy is greatest if you forget a tablet at the beginning or the end of the strip. Therefore, you should adhere to the following rules:

More than one tablet forgotten in this strip
Contact your doctor.

One tablet forgotten in week 1
Take the forgotten tablet as soon as you remember, even if that means that you have to take two tablets at the same time. Take the tablets again at the usual time and use extra precautions for the next 7 days, for example, a condom. If you have had intercourse in the week before the oversight or you have forgotten to start a new strip after the tablet-free period, you must realise that there is a risk of pregnancy. In that case, contact your doctor.

One tablet forgotten in week 2
Take the forgotten tablet as soon as you remember, even if that means that you have to take two tablets at the same time. Take the tablets again at the usual time. The protection from pregnancy is not reduced, given that you have taken the tablets correctly in the previous 7 days, otherwise extra precaution should be used for the next 7 days.

One tablet forgotten in week 3
You can choose between two possibilities:

  1. Take the forgotten tablet as soon as you remember, even if that means that you have to take two tablets at the same time. Take the tablets again at the usual time. Instead of the tablet-free period go straight on to the next strip.

Most likely, you will have a period (withdrawal bleed) at the end of the second strip but you may also have spotting or breakthrough bleeding during the second strip.

  1. You can also stop the strip and go directly to the tablet-free period of 7 days (record the day on which you forgot your tablet). If you want to start a new strip on your fixed start day, make the tablet-free period less than 7 days.

If you follow either of these two recommendations, you will remain protected against pregnancy.

If you have forgotten any of the tablets in a strip, and you do not have bleeding in the first tablet-free period, this may mean that you are pregnant. You must contact your doctor before you go on to the next strip.

If you are sick or taking other medications
What must you do in the case of vomiting or severe diarrhoea
If you vomit within 3-4 hours of taking a tablet or you have severe diarrhoea, there is a risk that the active substances in the pill are not fully adsorbed into your body. The situation is similar to if you forget a tablet. After vomiting or diarrhoea, you must take another tablet from a reserve strip as soon as possible. If possible take it within 12 hours of when you normally take your pill. If this is not possible or 12 hours have passed, you should follow the advice given under ‘if you forget to take Levest.’Effect on blood testsIf you need a blood test, tell your doctor or the laboratory staff that you are taking the pill, because oral contraceptives can affect the results of some tests.

Taking other medicines

Always tell the doctor, who prescribes Levest, which medicines or herbal products you are already using. Also tell any other doctor or dentist who prescribes another medicine (or the dispensing pharmacist) that you are using Levest. They can tell you if you need to take additional contraceptive precautions (for example condoms) and if so, for how long.

Some medicines can make Levest less effective in preventing pregnancy, or can cause unexpected bleeding. They include medicines used for the treatment of epilepsy (e,g, primidone, phenytoin, barbiturates, carbamazepine, oxcarbamazepine, topiramate, felbamate) and tuberculosis (e.g. rifampicin), or HIV infections (ritonavir, nevirapine) or other infectious diseases (griseofulvin, penicillin, tetracycline), medicines that increase the motility of your intestines (metoclopramide), and the herbal remedy St. John’s wort.

Levest may influence the effect of other medicines, e.g. medicines containing cyclosporin, or the anti-epileptic lamotrigine (this could lead to an increased frequency of seizures).

Ask your doctor or pharmacist for advice before taking any medicine.

Possible side effects
Like all medicines, Levest® can cause side effects, although not everybody gets them.Common side effects (affecting more than 1 in 100, but less than 1 in 10 women):
Mood swings, headache, abdominal pain (stomach ache), acne, breast pain, weight gain, nausea.Uncommon side effects (affecting more than 1 in 1000 but less than 1 in 100 women):
Vomiting, diarrhoea, fluid retention, migraine, decreased libido (interest in sex), breast enlargement, itchy red rash of the skin (urticaria).

Rare side effects (affecting less than 1 in 1000 women):
Contact lens intolerance, allergic reactions, weight loss, increased libido (interest in sex, breast discharge, vaginal discharge, allergic reactions which can sometimes be severe with swelling of the skin and/or mucous membranes (erythema nodosum & erythema multiforme).

Other serious side effects you should be aware of are also mentioned in section 2 of your Patient Information Leaflet.

These include:

  • Blood clot disorders
  • High blood pressure
  • Liver tumours
  • Swelling of the skin (angioedema)
  • Occurrence or deterioration of conditions such as: Crohn’s disease, epilepsy, migraine etc

Reporting side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in your Patient Information Leaflet. You can also report side effects directly via Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

Storing your Levest®
Keep out of the sight and reach of children. Store below 25° C.
Do not use Levest® after the expiry date which is stated on the carton.
The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Pack contents and information
Levest® tablets are white, circular, biconvex and sugar coated.
Each blister pack contains 21 tablets.Levest® is sold in cartons of 1, 3, 6 or 13 blister packs. Not all pack sizes may be marketed.Marketing Authorisation Holder
Morningside Healthcare Ltd
115 Narborough Road
Leicester, LE3 0PA
United Kingdom



  1. Morningside Healthcare Ltd. Levest 150/30 microgram Coated Tablets. Summary of Product Characteristics. June 2021. Available at: https://www.medicines.org.uk/emc/product/9565 (accessed July 2022);
  2. Bayer PLC. Microgynon 30 tablets. Summary of Product Characteristics. June 2020. Available at: https://www.medicines.org.uk/emc/product/1130 (accessed July 2022);
  3. MHRA. UK PAR Levonorgestrel/Ethinylestradiol 150/30 microgram coated tablets. Available at: https://mhraproductsproduction.blob.core.windows.net/docs/ca50b58c7d0d8c6fe9d2d53ec38d2d1f17ff7e1f (accessed July 2022);
  4. MHRA. UK PAR Femicept 150/30 coated tablets, Levest 150/30 coated tablets (levonorgestrel, ethinylestradiol). Available at: https://www.geneesmiddeleninformatiebank.nl/Pars/h102777.pdf (accessed July 2022).