Cimizt® – A low cost1-3, bioequivalent alternative to Marvelon®4,5

  • Cimizt® is a monophasic combined oral contraceptive (COC), containing 150mcg desogestrel and 30mcg ethinylestradiol
  • Cimizt® contains the same active ingredients and is bioequivalent to Marvelon®, therefore, following appropriate patient assessment and review, it may be prescribed in place of Marvelon®3-6
  • Each pack of Cimizt® contains 3 x blister strips of 21 tablets for 3 cycles of contraceptive cover7
cimizt
Please refer to the full Summary of Product Characteristics (SmPC) before prescribing.

Summary of Product Characteristics and Patient Information Leaflet
Summary of Product Characteristics:
https://www.medicines.org.uk/emc/product/9568/smpc

Patient Information Leaflet:
https://www.medicines.org.uk/emc/product/9568/pil

Additional Prescriber Resources
Whether your patient is starting the pill for the first time, or you are talking to her about changing from her current brand of contraceptive to Cimizt®, it can be useful to have information and materials to hand to counsel patients. The following assets can be downloaded/edited at your discretion for use during a consultation:

The full NICE Clinical Knowledge Summary for contraceptive prescribing for combined oral contraceptives, including UK Medical Eligibility Criteria may be found here.

 
References

  1. Data on File: Contraceptives Cost Saving Data. Feb 2019;
  2. MIMS. Marvelon (Merck Sharp & Dohme Ltd). Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/marvelon (accessed July 2020);
  3. Morningside Healthcare Ltd. Cimizt® PI. May 2020. CIM/PI/27333-0520;
  4. MHRA. UK PAR Cimizt 150 microgram/30 microgram tablets. Available at: https://mhraproductsproduction.blob.core.windows.net/docs/4a1ca9185731e16b811c8e44107621fcb279801e (accessed July 2020);
  5. Netherlands Medicines Evaluation Board. Public Assessment Report Desogestrel/Ethinylestradiol Famy 150/20 and 150/30 microgram tablets. August 2012. Available at: https://www.geneesmiddeleninformatiebank.nl/Pars/h108164.pdf (accessed July 2020);
  6. Merck Sharp & Dohme Ltd. Marvelon Tablets. Summary of Product Characteristics. December 2018. Available at: https://www.medicines.org.uk/emc/product/1359/smpc (accessed July 2020);
  7. MIMS. Cimizt. Available at: https://www.mims.co.uk/drugs/contraception/combined-contraceptives/cimizt (accessed July 2020).

Marvelon® chosen as a comparator as it is the license reference product for Cimizt®.4